8 research outputs found

    Wearable Computing for Health and Fitness: Exploring the Relationship between Data and Human Behaviour

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    Health and fitness wearable technology has recently advanced, making it easier for an individual to monitor their behaviours. Previously self generated data interacts with the user to motivate positive behaviour change, but issues arise when relating this to long term mention of wearable devices. Previous studies within this area are discussed. We also consider a new approach where data is used to support instead of motivate, through monitoring and logging to encourage reflection. Based on issues highlighted, we then make recommendations on the direction in which future work could be most beneficial

    Deep transformation models for functional outcome prediction after acute ischemic stroke

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    In many medical applications, interpretable models with high prediction performance are sought. Often, those models are required to handle semi-structured data like tabular and image data. We show how to apply deep transformation models (DTMs) for distributional regression which fulfill these requirements. DTMs allow the data analyst to specify (deep) neural networks for different input modalities making them applicable to various research questions. Like statistical models, DTMs can provide interpretable effect estimates while achieving the state-of-the-art prediction performance of deep neural networks. In addition, the construction of ensembles of DTMs that retain model structure and interpretability allows quantifying epistemic and aleatoric uncertainty. In this study, we compare several DTMs, including baseline-adjusted models, trained on a semi-structured data set of 407 stroke patients with the aim to predict ordinal functional outcome three months after stroke. We follow statistical principles of model-building to achieve an adequate trade-off between interpretability and flexibility while assessing the relative importance of the involved data modalities. We evaluate the models for an ordinal and dichotomized version of the outcome as used in clinical practice. We show that both, tabular clinical and brain imaging data, are useful for functional outcome prediction, while models based on tabular data only outperform those based on imaging data only. There is no substantial evidence for improved prediction when combining both data modalities. Overall, we highlight that DTMs provide a powerful, interpretable approach to analyzing semi-structured data and that they have the potential to support clinical decision making.Comment: Preprint under revie

    The potential of wearable technology for monitoring social interactions based on interpersonal synchrony

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    Sensing data from wearables have been extensively evaluated for fitness tracking, health monitoring or rehabilitation of individuals. However, we believe that wearable sensing can go beyond the individual and offer insights into social dynamics and interactions with other users by considering multi-user data. In this work, we present a new approach to using wrist-worn wearables for social monitoring and the detection of social interaction features based on interpersonal synchrony - an approach transferable to smartwatches and fitness trackers. We build up on related work in the field of psychology and present a study where we collected wearable sensing data during a social event with 24 participants. Our preliminary results indicate differences in wearable sensing data during a social interaction between two people

    Modernisierungskonzept der Architektur von iBEAM

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    Interaction Design for Semi-Public Ambient Displays with Mobile and Motion-Tracking Components

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    nicht vorhande

    HEALTHI: Workshop on Intelligent Healthy Interfaces

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    The second workshop on intelligent healthy interfaces (HEALTHI), collocated with the 2022 ACM Intelligent User Interfaces (IUI) conference, offers a forum that brings academics and industry researchers together and seeks submissions broadly related to the design of healthy user interfaces. The workshop will discuss intelligent user interfaces such as screens, wearables, voices assistants, and chatbots in the context of accessibly supporting health, health behavior, and wellbeing

    Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA.

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    Current evidence suggests that plasma cell-free DNA (cfDNA) is fragmented around a mode of 166 bp. Data supporting this view has been mainly acquired through the analysis of double-stranded cfDNA. The characteristics and diagnostic potential of single-stranded and damaged double-stranded cfDNA in healthy individuals and cancer patients remain unclear. Here, through a combination of high-affinity magnetic bead-based DNA extraction and single-stranded DNA sequencing library preparation (MB-ssDNA), we report the discovery of a large proportion of cfDNA fragments centered at ∌50 bp. We show that these "ultrashort" cfDNA fragments have a greater relative abundance in plasma of healthy individuals (median = 19.1% of all sequenced cfDNA fragments, n = 28) than in plasma of patients with cancer (median = 14.2%, n = 21, P < 0.0001). The ultrashort cfDNA fragments map to accessible chromatin regions of blood cells, particularly in promoter regions with the potential to adopt G-quadruplex (G4) DNA secondary structures. G4-positive promoter chromatin accessibility is significantly enriched in ultrashort plasma cfDNA fragments from healthy individuals relative to patients with cancers (P < 0.0001), in whom G4-cfDNA enrichment is inversely associated with copy number aberration-inferred tumor fractions. Our findings redraw the landscape of cfDNA fragmentation by identifying and characterizing a novel population of ultrashort plasma cfDNA fragments. Sequencing of MB-ssDNA libraries could facilitate the characterization of gene regulatory regions and DNA secondary structures via liquid biopsy. Our data underline the diagnostic potential of ultrashort cfDNA through classification for cancer patients
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